<p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Axitinib</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="400" data-end="403"><em data-start="405" data-end="500">This cancer treatment can interact with other medicines and may require specialist oversight.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Benzodiazepines</span></strong><span class="apple-converted-space"><span style="font-family: Calibri, sans-serif;">&nbsp;</span></span><span style="font-family: Calibri, sans-serif;">(such as diazepam, temazepam, or lorazepam)<br data-start="567" data-end="570"><em data-start="572" data-end="674">These medicines affect the central nervous system and may increase drowsiness or other side effects.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Carbamazepine</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="695" data-end="698"><em data-start="700" data-end="812">This medicine can reduce the effectiveness of other treatments by altering how they are processed in the body.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Fluvoxamine</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="831" data-end="834"><em data-start="836" data-end="913">This antidepressant can significantly affect the levels of other medicines.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Leflunomide</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="932" data-end="935"><em data-start="937" data-end="1040">This medicine affects the immune system and may increase the risk of adverse effects or interactions.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Oestrogen-containing medicines</span></strong><span class="apple-converted-space"><span style="font-family: Calibri, sans-serif;">&nbsp;</span></span><span style="font-family: Calibri, sans-serif;">(including hormone replacement therapy or the combined oral contraceptive pill)<br data-start="1158" data-end="1161"><em data-start="1163" data-end="1257">These medicines can interact with certain treatments and may affect safety or effectiveness.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Pipemidic acid</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="1279" data-end="1282"><em data-start="1284" data-end="1373">This antibiotic may interact with other medicines or increase the risk of side effects.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Quinolone or fluoroquinolone antibiotics</span></strong><span class="apple-converted-space"><span style="font-family: Calibri, sans-serif;">&nbsp;</span></span><span style="font-family: Calibri, sans-serif;">(such as ciprofloxacin)<br data-start="1445" data-end="1448"><em data-start="1450" data-end="1550">These antibiotics can interact with other medicines and, in some cases, affect the nervous system.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Rifampicin</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="1568" data-end="1571"><em data-start="1573" data-end="1681">This medicine strongly affects how many other drugs are broken down, which can reduce their effectiveness.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Teriflunomide</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="1702" data-end="1705"><em data-start="1707" data-end="1807">This immune-modifying medicine can interact with other treatments and requires careful monitoring.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Warfarin or other blood-thinning (anticoagulant) medicines</span></strong><span style="font-family: Calibri, sans-serif;"><br data-start="1873" data-end="1876"><em data-start="1878" data-end="1990">These medicines increase bleeding risk and often require close monitoring when combined with other treatments.</em><o:p></o:p></span></p><p style="margin-right: 0cm; margin-left: 18pt; font-size: medium; font-family: &quot;Times New Roman&quot;, serif; caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0);"><strong><span style="font-family: Calibri, sans-serif;">Z-drugs or sleeping tablets</span></strong><span class="apple-converted-space"><span style="font-family: Calibri, sans-serif;">&nbsp;</span></span><span style="font-family: Calibri, sans-serif;">(such as zopiclone or zolpidem)<br data-start="2057" data-end="2060"><em data-start="2062" data-end="2174">These medicines can increase drowsiness and may interact with other treatments that affect sleep or alertness.</em><o:p></o:p></span></p>